|David A. Ziegler, Ph.D.
UCSF - Mission Bay
Sandler Neuroscience Research Building, Rm 505
MC 0444, 675 Nelson Rising Lane
San Francisco, CA 94158
Biography: Dr. Ziegler completed his
Ph.D. in Systems Neuroscience in the Department of Brain and Cognitive Sciences
at the Massachusetts Institute of Technology where he took a cutting-edge
multimodal neuroimaging approach to examine the effects of healthy aging and
Parkinson’s disease on cognitive control systems in the brain. The current
focus of his research is on unmasking the neural mechanisms that account for
age-related changes in cognitive control and to translate these basic neuroscience
findings into cognitive neurotherapeutic interventions to alleviate impairments
in attention in diverse populations. He has a particular interest in merging
complementary mind-body approaches, such as meditation and yoga, with
neuroplasticity-based interventions to improve cognition while also enhancing
overall wellbeing. Dr. Ziegler has received numerous awards, including a UCSF
School of Medicine Technology Transformation Grant, a Human Brain Mapping
Trainee Travel Award, the Angus MacDonald Award for Excellence in Undergraduate
Teaching at MIT, the Denison University President’s Medal, and was a two-time
recipient of the Harvard/MIT/MGH Advanced Multimodal Neuroimaging Training
Program Fellowship. His research has been featured in The New York Times, the Faculty of 1000, the MIT Spotlight, Nature Outlook, and in
numerous regional media outlets.
Ziegler DA, Mishra J, Gazzaley A. (in press). The acute and chronic impact of technology on our brain. in Rosen LD, Carrier LM, & Cheever NA (Eds). The Handbook of Psychology, Technology, and Society.
Ziegler DA, Ashourian P, Griffith EY, Hansen LA, Hämäläinen M,
Corkin S. (in revision). Age-related changes in white matter integrity
disrupt top-down modulation of oscillations during visual search.
Ziegler DA, Ashourian P, Wonderlick JS, Prelec D, Scherzer CS, Corkin S (2014). Motor Impulsivity in Parkinson Disease: Associations with COMT and DRD2 polymorphisms. Scand J Psychol, 55: 278-86. [pubmed]
Mishra J, Anguera JA, Ziegler
DA, Gazzaley A. (2013). A cognitive framework for understanding and improving interference resolution in the brain. Prog Brain Res, 207: 351-377. [pdf][pubmed]
Ziegler DA and Corkin S. (2013). New MRI biomarkers
advance the characterization of Parkinson disease. European Neurological Review, 9: 8–12. [pubmed]
DA and Augustinack JC. (2013). Harnessing advances
in structural MRI to enhance research on Parkinson's disease. Imaging in Medicine, 5: 91-94. [pdf][pubmed]
Ziegler DA, Wonderlick JS, Ashourian P, Hansen LA, Young JC,
Murphy AJ, Kopuzha CK, Growdon JH, Corkin S. (2013). Substantia
nigra volume loss before basal forebrain degeneration in early
Parkinson's disease. JAMA Neurology, 70(2):241-7. [pdf] [pubmed]
Ziegler DA and Corkin S. (2013). New Magnetic Resonance Imaging biomarkers advance the characterization of Parkinson disease. US Neurology, 9: 8–12. [pdf]
O'Brien LM, Ziegler DA, Herbert MR, Deutsch CK, Frazier JA.
(2011). Adjustment for head size differences in volumetric MRI studies:
theoretical issues and practical implications. Psychiatry Research:
Neuroimaging, 193(2): 113-122. [pdf]
Ziegler DA, Piquet O, Salat DH, Prince K, Connally E, Corkin S.
(2010). Cognition in healthy aging is related to regional white matter
integrity, but not cortical thickness. Neurobiol Aging, 31(11): 1912-26.
Ziegler DA, Pritchett DL, Hosseini-Varnamkhasti P, Corkin S,
Hämäläinen M, Moore CI, Jones SR. (2010). Transformations in oscillatory
activity and evoked responses in primary somatosensory cortex in middle
age: A combined computational neural modeling and MEG study. NeuroImage,
52(3): 897-912. [pdf][pubmed]
Wonderlick JS, Ziegler DA, Hosseini-Varnamkhasti P, Bakkour A,
van der Kouwe A, Triantafyllou C, Corkin S, Dickerson BC. (2009).
Reliability of MRI-derived cortical and subcortical morphometric
measures: Effects of pulse sequence, voxel geometry, and parallel
imaging. NeuroImage, 44(4): 1324-33. [pdf]
O'Brien LM, Ziegler DA, Deutsch CK, Kennedy DN, Goldstein J,
Seidman L, Hodge S, Makris N, Caviness VS, Frazier J, Herbert MR.
(2006). Adjustment for whole brain and cranial size in volumetric brain
studies: a review of common adjustment factors and statistical methods.
Harvard Review of Psychiatry, 14: 141-151. [pdf][pubmed]
Herbert MR, Ziegler DA, Deutsch CK, O'Brien LM, Kennedy DN,
Filipek PA, Bakardjiev A, Hodgson J, Takeoka M, Makris N, Caviness VS
Jr. (2005). Brain asymmetries in autism and developmental language
disorder: A nested multi-level analysis. Brain, 128. 213-226. [pdf][pubmed]
Herbert MR, Ziegler DA, Makris N, Filipek PA, Normandin JJ,
Sanders HA, Kennedy DN, Caviness VS Jr. (2004). Localization of white
matter volume increase in autism and developmental language disorder.
Annals of Neurology, 55. 530-540. [pdf][pubmed]
Makris N, Gasic GP, Seidman, LJ, Goldstein JM, Gastfriend DR, Elman I,
Albaugh DM, Hodge SM, Ziegler DA, Sheahan F, Caviness VS Jr,
Tsuang MT, Kennedy DN, Hyman SE, Rosen BR, Brieter HC. (2004). Decreased
absolute amygdala volume in cocaine addicts. Neuron, 44. 729-740. [pdf][pubmed]
De Fosse L, Hodge SM, Makris N, Kennedy DN, Caviness VS Jr, McGrath L,
Steele S, Ziegler DA, Herbert MR, Frazier J, Tager-Flusberg H,
Harris GJ. (2004).Language-association cortex asymmetry in autism and
specific language impairment. Annals of Neurology, 56(6). 757-766. [pdf][pubmed]
Herbert MR, Ziegler DA, Deutch CK, O'Brien LM, Lange NT,
Bakardjiev A, Hodgson J Adrien KT, Steele S, Makris N, Kennedy DN,
Harris GJ, Caviness VS Jr. (2003). Dissociations of cerebral cortex,
subcortical, and cerebral white matter volumes in autistic boys. Brain,
126 (5). 1182-1192. [pdf][pubmed]
Herbert MR, Harris GJ, Adrien KT, Ziegler DA, Makris N, Kennedy
DN, Lange NT, Chabris, CF, Bakardjiev A, Hodgson J, Takeoka M,
Tager-Flusberg H, Caviness VS Jr. (2002). Abnormal asymmetry in language
association cortex in autism. Annals of Neurology, 52. 588-596. [pdf][pubmed]