David A. Ziegler, Ph.D.


UCSF - Mission Bay
Sandler Neuroscience Research Building, Rm 505
MC 0444, 675 Nelson Rising Lane
San Francisco, CA 94158





Curriculum Vitae


Dr. Ziegler completed his Ph.D. in Systems Neuroscience in the Department of Brain and Cognitive Sciences at the Massachusetts Institute of Technology where he took a cutting-edge multimodal neuroimaging approach to examine the effects of healthy aging and Parkinson’s disease on cognitive control systems in the brain. The current focus of his research is on unmasking the neural mechanisms that account for age-related changes in cognitive control and to translate these basic neuroscience findings into cognitive neurotherapeutic interventions to alleviate impairments in attention in diverse populations. He has a particular interest in merging complementary mind-body approaches, such as meditation and yoga, with neuroplasticity-based interventions to improve cognition while also enhancing overall wellbeing. Dr. Ziegler has received numerous awards, including a UCSF School of Medicine Technology Transformation Grant, a Human Brain Mapping Trainee Travel Award, the Angus MacDonald Award for Excellence in Undergraduate Teaching at MIT, the Denison University President’s Medal, and was a two-time recipient of the Harvard/MIT/MGH Advanced Multimodal Neuroimaging Training Program Fellowship. His research has been featured in The New York Times, the Faculty of 1000, the MIT Spotlight, Nature Outlook, and in numerous regional media outlets.

Selected Publications
  1. Ziegler DA, Mishra J, Gazzaley A. (in press). The acute and chronic impact of technology on our brain. in Rosen LD, Carrier LM, & Cheever NA (Eds). The Handbook of Psychology, Technology, and Society.
  2. Ziegler DA, Ashourian P, Griffith EY, Hansen LA, Hämäläinen M, Corkin S. (in revision). Age-related changes in white matter integrity disrupt top-down modulation of oscillations during visual search.
  3. Ziegler DA, Ashourian P, Wonderlick JS, Prelec D, Scherzer CS, Corkin S (2014). Motor Impulsivity in Parkinson Disease: Associations with COMT and DRD2 polymorphisms. Scand J Psychol, 55: 278-86.[pubmed]
  4. Mishra J, Anguera JA, Ziegler DA, Gazzaley A. (2013). A cognitive framework for understanding and improving interference resolution in the brain. Prog Brain Res, 207: 351-377.[pubmed]
  5. Ziegler DA and Corkin S. (2013). New MRI biomarkers advance the characterization of Parkinson disease. European Neurological Review, 9: 8–12. [pubmed]
  6. Ziegler DA and Augustinack JC. (2013). Harnessing advances in structural MRI to enhance research on Parkinson's disease. Imaging in Medicine, 5: 91-94. [pubmed]
  7. Ziegler DA, Wonderlick JS, Ashourian P, Hansen LA, Young JC, Murphy AJ, Kopuzha CK, Growdon JH, Corkin S. (2013). Substantia nigra volume loss before basal forebrain degeneration in early Parkinson's disease. JAMA Neurology, 70(2):241-7. [pubmed]
  8. Ziegler DA, Wonderlick JS, Ashourian P, Hansen LA, Young JC, Murphy AJ, Kopuzha CK, Growdon JH, Corkin S. (2013). Substantia nigra volume loss before basal forebrain degeneration in early Parkinson's disease. JAMA Neurology, 70(2):241-7. [pubmed]
  9. Ziegler DA and Corkin S. (2013). New Magnetic Resonance Imaging biomarkers advance the characterization of Parkinson disease. US Neurology, 9: 8–12.
  10. O'Brien LM, Ziegler DA, Herbert MR, Deutsch CK, Frazier JA. (2011). Adjustment for head size differences in volumetric MRI studies: theoretical issues and practical implications. Psychiatry Research: Neuroimaging, 193(2): 113-122. [pubmed]
  11. Ziegler DA, Piquet O, Salat DH, Prince K, Connally E, Corkin S. (2010). Cognition in healthy aging is related to regional white matter integrity, but not cortical thickness. Neurobiol Aging, 31(11): 1912-26. [pubmed]
  12. Ziegler DA, Pritchett DL, Hosseini-Varnamkhasti P, Corkin S, Hämäläinen M, Moore CI, Jones SR. (2010). Transformations in oscillatory activity and evoked responses in primary somatosensory cortex in middle age: A combined computational neural modeling and MEG study. NeuroImage, 52(3): 897-912. [pubmed]
  13. Wonderlick JS, Ziegler DA, Hosseini-Varnamkhasti P, Bakkour A, van der Kouwe A, Triantafyllou C, Corkin S, Dickerson BC. (2009). Reliability of MRI-derived cortical and subcortical morphometric measures: Effects of pulse sequence, voxel geometry, and parallel imaging. NeuroImage, 44(4): 1324-33. [pubmed]
  14. O'Brien LM, Ziegler DA, Deutsch CK, Kennedy DN, Goldstein J, Seidman L, Hodge S, Makris N, Caviness VS, Frazier J, Herbert MR. (2006). Adjustment for whole brain and cranial size in volumetric brain studies: a review of common adjustment factors and statistical methods. Harvard Review of Psychiatry, 14: 141-151. [pubmed]
  15. Herbert MR, Ziegler DA, Deutsch CK, O'Brien LM, Kennedy DN, Filipek PA, Bakardjiev A, Hodgson J, Takeoka M, Makris N, Caviness VS Jr. (2005). Brain asymmetries in autism and developmental language disorder: A nested multi-level analysis. Brain, 128. 213-226. [pubmed]
  16. Herbert MR, Ziegler DA, Makris N, Filipek PA, Normandin JJ, Sanders HA, Kennedy DN, Caviness VS Jr. (2004). Localization of white matter volume increase in autism and developmental language disorder. Annals of Neurology, 55. 530-540. [pubmed]
  17. Makris N, Gasic GP, Seidman, LJ, Goldstein JM, Gastfriend DR, Elman I, Albaugh DM, Hodge SM, Ziegler DA, Sheahan F, Caviness VS Jr, Tsuang MT, Kennedy DN, Hyman SE, Rosen BR, Brieter HC. (2004). Decreased absolute amygdala volume in cocaine addicts. Neuron, 44. 729-740. [pubmed]
  18. De Fosse L, Hodge SM, Makris N, Kennedy DN, Caviness VS Jr, McGrath L, Steele S, Ziegler DA, Herbert MR, Frazier J, Tager-Flusberg H, Harris GJ. (2004).Language-association cortex asymmetry in autism and specific language impairment. Annals of Neurology, 56(6). 757-766.[pubmed]
  19. Herbert MR, Ziegler DA, Deutch CK, O'Brien LM, Lange NT, Bakardjiev A, Hodgson J Adrien KT, Steele S, Makris N, Kennedy DN, Harris GJ, Caviness VS Jr. (2003). Dissociations of cerebral cortex, subcortical, and cerebral white matter volumes in autistic boys. Brain, 126 (5). 1182-1192. [pubmed]
  20. Herbert MR, Harris GJ, Adrien KT, Ziegler DA, Makris N, Kennedy DN, Lange NT, Chabris, CF, Bakardjiev A, Hodgson J, Takeoka M, Tager-Flusberg H, Caviness VS Jr. (2002). Abnormal asymmetry in language association cortex in autism. Annals of Neurology, 52. 588-596. [pubmed]